EACH CAPSULE CONTAINS:
- Rabeprazole sodium 20 mg
- Levosulpride 75 mg
Rabeprazole is a rapid acting proton pump inhibitor (PPI). Rabeprazole is a substituted benzimidazole which suppresses gastric acid secretion by inhibiting the gastric H+/ K+ ATPase at the secretory surface of the gastric parietal cell. This enzyme is regarded as the acid (proton) pump within the parietal cell. Rabeprazole blocks the final step of gastric acid secretion.
Levosulpiride is more selective and acts primarily as dopamine D2 antagonist.it is also a moderate agonist at 5-HT receptor.Its 5-HT4 component may enhance its therapeutic efficacy in GI disorders.This property together with antagonism at D2 receptor may contribute to its GI prokinetic effect.